Potential Candidates for Prophylactic MastectomyA question that women ask is when they need to undergo prophylactic mastectomy. A woman may consider this procedure in the following conditions…
- Strong family history of breast cancer = More than one relative, including the mother, daughter or sister, diagnosed with the disease before the age of 50
- Positive genetic testing for the gene mutations BRCA1, BRCA2, CDH1, PALB2, PTEN, or TP53
- Previous history of breast cancer = Higher risk of developing cancer in the opposite breast
- Prior diagnosis of Lobular Carcinoma In Situ (LCIS) = Increased risk of developing invasive breast cancer
- Prior chest radiation therapy before the age of 30
- Numerous, widely spread microcalcifications in the breast on mammogram = Repeated occurrences of these microcalcifications increase the risk of developing breast cancer
The Benefits and Disadvantages of Prophylactic MastectomyAccording to the National Cancer Institute in the U.S., prophylactic mastectomy can reduce the risk of a woman’s developing cancer by 90 percent. It does not mean though that a woman is completely protected from breast cancer. Also, the women who benefit most from this procedure are those with the BRCA1 and BRCA2 mutations who are in their 30s, with 3 to 5 years added to their lifespan. Women with these same mutations who are 60 years old and older have only a minimal gain in their lifespan. Prophylactic mastectomy is also not without its risks, including the risk of infection that accompanies every major surgery. There is also the matter of cost. Genetic testing for the BRCA mutation costs an estimated Singaporean $6,000. Prophylactic mastectomy and breast reconstruction is estimated at Singaporean $50,000. Any woman contemplating prophylactic mastectomy should seek medical advice with her breast surgeon in order to get more information about this procedure.
Currently, Dr Evan is one of a handful of surgeons in Singapore able to offer both the full range of options in breast cancer removal (lumpectomy / breast conservation surgery / oncoplastic breast surgery), and the full gamut of reconstructive options after both breast removal or breast conservation surgery (including use of perforator flap-free tissue transfer). This ensures a truly integrated and comprehensive breast surgery practice.